Customised DNA-Encoded Libraries

Delivering high quality hits fast and cost-efficient

Serengen enables the fastest and most economical unbiased hit identification that allows for serendipity, by meeting your quality and speed requirements and your cost targets.

Truly druglike and high potential DELs

Overcome the bottlenecks of unbiased screening technologies:
Serengen’s DELs deliver high-quality hits fast and cost-efficient.

Serengen is your partner for hit identification

We adapt to your needs and develop your individual solution.

CUSTOMISED DEL SYNTHESIS

DEL SELECTION SCREENING

Unbiased design (diversity-focused DEL)
Semi-unbiased design (scaffold-focused DEL)
Structure-enabled design (target-focused DEL)
Ligand-enabled design (hit-expansion DEL)

Affinity matrix screening
Wide range of proteins
Enrichment calculation
Double control

MOLECULAR CLASSES

TARGET CLASSES

Small molecules
Short peptides
Peptidomimetics
Macrocycles
… and more

Membrane-bound proteins
PPIs
Enzymes
Transcription factors
… and more

CUSTOMISED DEL SYNTHESIS

Unbiased design (diversity-focused DEL)
Semi-unbiased design (scaffold-focused DEL)
Structure-enabled design (target-focused DEL)
Ligand-enabled design (hit-expansion DEL)

DEL SELECTION SCREENING

Affinity matrix screening
Wide range of proteins
Enrichment calculation
Double control

Molecular classes

Small molecules
Short peptides
Peptidomimetics
Macrocycles
… and more

Target classes

Membrane-bound proteins
PPIs
Enzymes
Transcription factors
… and more

WHY SERENGEN?

BREAKTHROUGH
TECHNOLOGY

Novel proprietary encoding strategy based on stabilised DNA.

UNPARALLELED
FLEXIBILITY

Tailor-made DELs through wide range of chemical reactions

NEW CHEMICAL
SPACE

High potential to address new targets

NOVEL
APPROACH

No redundancy, reduced costs, fast progression

Get in touch

Call us on +49 (0)231 999 50 902